Webinar Overview

As antibody-drug conjugates evolve toward more complex architectures such as bispecific and dual-payload ADCs, traditional analytical methods are increasingly challenged in accurately characterizing critical quality attributes (CQAs). In this webinar, Dr. Zhao will focus on the development of robust analytical strategies to address these complexities. Key topics include drug-to-antibody ratio (DAR) determination, drug loading distribution profiling, free drug and charge variant analysis for novel ADC formats. Attendees will gain practical insights into building fit-for-purpose analytical platforms, overcoming common method development hurdles, and ensuring reliable CQA measurement to support the advancement of next-generation ADCs.

Key Learning Objectives

    · Learn analytical strategies for novel ADC characterization

    · Explore DAR and drug load distribution analysis

    · Understand free drug and charge variant analysis

    ·  Apply fit-for-purpose analytical approaches for reliable CQA measurement

Speaker Biography

Jinsong Zhao, Ph.D.

Senior Director, Analytical Development Department, AsymBio